Showing posts with label Derm round. Show all posts
Showing posts with label Derm round. Show all posts

Saturday, June 23, 2007

Derm round 24

45 years old lady presented with fever of 5 days duration, associated with chills, rigors, nausea, and bodyache. There was history of dengue outbreak in neighborhood. At day 5, fever resolved and the above rashes appeared mostly over her arms.

Clinically, multiple red spots with rim of halo noted over her arms. Full blood count showed leucopenia with lymphocytosis and thrombocytopenia, consistent with viral picture. Dengue IgM was positive.

Monday, March 5, 2007

Derm round 23

A 70 years old man was referred to the clinic for further management of multiple pruritic rashes over the body and lower limbs of two years duration.
The lesions over the body and lower limbs appeared well-demarcated erythematous rashes with scaling and excoriation. In addition, he has generalized skin dryness (xerosis).
I would have dismissed the case as 'another chronic eczema', until I find these lesions over the anterior chest.
A large ring-like lesion with central paling. There was reduced pin-prick sensation.
He also has this hand appearance, fixed flexion deformities of the right 4th and 5th fingers; suggesting of an ulna nerve lesion. The ulna nerve was thick on palpation. In addition, he has sparce eyebrows.
Slit-skin smears confirmed the diagnosis.
(Pic taken with my SE750)

Wednesday, February 28, 2007

Derm round 22



13 months old baby boy was admitted to the ward for prolonged fever. Clinically, he has hepato-splenomegaly. Full blood count showed pancytopenia. Peripheral blood film and the bone marrow aspirate were unremarkable. "Biohazard" screenings were all negative. Blood C&S has no growth and the rest of the investigations were unremarkable.

He was treated empirically with IV antibiotic (Cloxacillin and Ceftriaxone). After one week in the ward, and the temperature was still spiking, he developed numerous small papular lesions over the body and more marked over the lower limbs.

On examination, there were monomorphic, skin-colored, small papular eruptions, scattered over the face, body, upper limbs and numerously over the lower limbs (see pictures).

What is it?
We were thinking, more of molluscum contagiosum.

But the paediatricians thought otherwise, ? Gianotti-Crosti syndrome.

See:
eMedicine
DermNet NZ

Saturday, February 24, 2007

Derm round 20



27 years old gentleman presented with the above erythematous rashes over the malar region and alopecia of one year duration. There was no photosensitivity, oral ulcer or joint pain. Review of other system was unremarkable.

On examination, there was erythematous and slightly scaly lesion over the malar eminence as well as over the scalp. Similar lesions were also noted over the forearms and the back of trunk with areas of scarring. In addition, there was also scarring alopecia noted.

Diagnosis?
Discoid lupus.

More:
DermNet NZ
DermAtlas
BAD
lupus.org.uk

Friday, February 23, 2007

Derm round 19




50 years old gentleman, presented to me with the above lesions over his hands and feet of one month duration. He gave history of washing the floor mat with concentrated bleach solution three days before he started developing such lesions. He also stepped on the mat as well.

Clinically, the lesions appeared well-defined, dried and scaly with cracks, on an erythematous base. There were also maculo-papular rashes over the body. There was no scalp involvement or nail changes. Fungal scrapping was negative.

Although from the history, it sounded like contact dermatitis, clinically, the lesions appeared more "psoriatic". Furthermore, the lesions were more extensive and involved other non-exposure sites (body).

Diagnosis?
?Allergic contact dermatitis.
?Psoriasiform dermatitis.

Anyway, I treated him as having contact dermatitis.

Thursday, February 22, 2007

Derm round 18



46 years old lady presented with the above very pruritic lesions over the body of two months duration. She is a hawker selling Char Koay Teow by the road side. On examination, there were extensive papular lesions over the forearms, lower limbs, neck and body especially over the sun exposed areas.

Diagnosis?
We are treating her as having some form of photodermatitis or polymorphic light eruption.

She was given Betnovate 1:6 cream, aques cream as emollient and anti-histamine. However, her response was unsatisfactory, with persistent disturbing pruritic lesions. One factor contributing to her condition was, she still works by the roadside and wear T-shirt with short pants despite been advice against doing so.

Any comment or suggestion?

More:
BAD
eMedicine

Saturday, February 17, 2007

Derm round 17

50 years old gentleman, presented with right gluteal swelling of one year duration. The swelling bled easily on physical contact. He had symptoms of anaemia with loss of weight but normal apetite.

Clinically, the tumor is cauliflower-liked with ulceration and area of bleeding spots.

He was referred to dermatologist for opinion because of the HPE report:
Section showed skin with underlying spindle shaped illed-define lesion. The cells show a storiform pattern of arrangement. The cells have moderately pleomorphic muclei and few mitotic figures are seen. Foamy macrophages are noted with occasional large bizarre cells. The is no necrosis noted. There is no evidence of malignancy in this biopsy. Diagnosis: Benign fibrous histiocytoma.

However clinically, the lesion looked aggressive. There were multiple inguinal lymph nodes felt. No organomegaly felt. His Hb was 5.9 gm/dl. Other blood investigations were unremarkable. His chest X-ray was normal. CT scan of the lesion showed a soft tissue mass arising from the skin. CT scan chest/abdomen/pelvis revealed multiple lung nodules, inguinal lymphadenopathy and right ilium bone erosion.

In view of the clinical findings, this tumour behaved as malignant with evidence of metastasis.

A repeat biopsy was done on 13/2/2007.

Read:
Fibrous histiocytoma
Atlas of genetics and cytogenetics in oncology and haematology
GpNotebook
Malignant fibrous histiocytoma




Update (2/3/2007):
Repeat biopsy report:
Sections show skin tissue with underlying dermis. A diffuse cellular lesion is noted in the dermis. The lesion composed of spindle-shaped cells arranged in stori-form pattern. The spindle-shaped to plump cells exhibit mild to moderate pleomorphic vesicular nuclei and prominent nucleoli. Mitotic figures are seen. Infiltration by acute and chronic inflammatory cells is noted.
Immunohistochemical stain: The spindle-shaped cells are positive for vimentin.
Diagnosis: Dermatofibrosarcoma protuberans.

Thursday, February 15, 2007

Derm round 16







Diagnosis?
Acute generalized erythematous pustulosis (AGEP).

The above patient was admitted for an elective surgery of left obstructive uropathy due to ureteric calculi. On third day, she developed spiking temperature in the ward, and thus the procedure was cancelled. She was empirically started on IV Cefoperazone. She then developed the above small pustular lesion over the limbs as well as some scattered lesions over the trunk after two days. Blood investigations were unremarkable.

On review of her old notes, she was diagnosed as having AGEP two months before, and responded to a course of oral Itraconazole.

Assuming that she might be having similar candida infection, she was prescribed Itraconazole again. However, the lesions resolved completely the next day before Itraconazole was managed to be given. The antibiotic was stopped and she became afebrile.

Is the AGEP due to Cefoperazone or due to infection?



More:
AGEP due to herbal remedy.
IJDVL.
Archieve of Dermatology.
RegiScar Project.
Rev. Inst. Med trop. S. Paulo.
Dermatology Online Journal.
Medscape.

Derm round 15

Case 1


14 years old girl, had the above lesions since birth.

Diagnosis?
Congenital nevomelanocytic nevus, giant.

See also:
Congenital nevi.


Case 2
45 years old gentleman presented with the above pruritic lesion over the scrotum. Fungal scrapping was negative.

Diagnosis?
Lichen simplex chronicus.

Monday, February 12, 2007

Derm round 14

This eight years old boy has the above non-pruritic scalp lesions since infancy. He currently presented because the mother noted significant hair loss of one month duration. The lesions are very scaly plague with ill-defined borders. Wood's lamp and fungal scrapping were negative.

What is it?
I treated the patient for Seborrheic capitis (seborrheic dermatitis of the scalp).

Derm round 13

This 9 years old girl, presented with the above non-pruritic lesion of 2 months duration. It is a well-defined, slightly erythematous and scaly lesion. Wood's lamp was negative and fungal scrapping was negative.

What is it?
? Pityriasis alba.

What other differentials?

By the way, I gave her Hydrocortisone ointment.

Wednesday, February 7, 2007

Derm round 12


30 years old man presented with the above lesions over the supra-pubic/base of penis since the age of 18 years old (12 years). He denied history of sexual exposure when he first had the lesions.

These lesions looked something like this one too.

What is the diagnosis?
?Viral wart.

Below, I included some viral wart pictures from DermNet.com:





Tuesday, February 6, 2007

Derm round 11

65 years old lady presented with the above lesions over the face of 6 months duration.

What are these lesions?
? Granuloma faciale.

We did a biopsy and the result came back as such:
" Multiple sections showed skin tissue with marked granulomatous lesion in the dermis consists of aggregates of epitheliod cells, lymphocytes and some multinucleated giant cells. No obvious central caseous necrosis seen. No atypical cell seen. No evidence of malignancy seen. Stains for fungal, AFB and leprae bacilli are negative. Diagnosis: Chronic granulomatous lesion, suggestive of atypical mycobacterial infection."

Hmn, rather non-specific isn't is?
What features actually point to atypical mycobacterial infection, huh?
Anyway, we will discuss the case in the HPE discussion session with the pathologists cm.

Saturday, February 3, 2007

Derm round 10


The same lady with ?deep fungal infection (Derm round 4, case 2), was discharged and followed up in the clinic. The initial swab C&S grew Staphylococcus aureus (Sensitive to Cloxacillin). She was treated earlier with IV Unasyn and Metronidazole for one week. She had also been given two weeks of oral Cloxacillin.

Currently, the lesions appeared to have dried up, but her left foot was still edematous. There were thick scale-like lesions on her left foot, which bled on removal of the scales.

Still unsure what this lesions were due to. I was comtemplating to do a skin biopsy next.

Derm round 9

20 years old gentleman presented with the above slightly painful, pruritic and smelly lesions over the the soles of three days duration. He is a kitchen helper.
Fungal scrapping was negative.

What is it?

? Pitted keratolysis as well.
I gave him a course of oral Erythromycin, KMNO4 soak and anti-fungal cream.

Derm round 8

25 years old lady presented with the above lesions over the posterior neck region of 5 years duration.

The lesions appeared warty or cauliflower-like.

What is it?

?Viral wart.
?Epidermal naevus.

Tuesday, January 23, 2007

Derm round 7

Case 1

25 years old man presented with the above lesions of three weeks duration.

Diagnosis?
Pitted keratolysis.

More:
DermNet NZ.
eMedicine.

Case 2

58 years old lady, with history of right breast CA and mastectomy done, developed the above lesions after given two cycles of chemotherapy.

Diagnosis?
?Vitiligo

Case 3
65 years old man presented with the above painful lesions over the anterior chest wall with small vesicles and discharges. He was told by the GP that it was shingles. Patient was very concerned and decided to seek 2nd opinion.

The lesion appeared in a straight line, with areas of crusting and serous discharge. It did not confine to a typical dermatomal area.

Diagnosis?
Most likely insect bite reaction.

Case 4

29 years old guy, presented with the above non-pruritic rashes over three weeks duration over the body, first started over the left shin.

On examination, there was scattered ring-liked erythematous papules with skight scaling over the back of the trunk. There was also a bigger such lesion over the left shin. Fungal scrapping was negative.

Diagnosis?
Pityriasis rosea (Note the herald patch).

Case 5
25 years old lady presented with the above pigmented lesions over the back of three years duration, which were non-pruritic.

On inspection, there was areas of reticular hyperpigmented macules with fine scaling seen.
Fungal scrapping was negative.

Diagnosis?
Initially thought it was Pityriasis vesicolor, however scrapping was negative.
My friend suggested that it could be Becker's naevus. (However, I didn't see obvious overlying hair).
The above lesions were noted on the body of a 55 years old man. He is asymptomatic. He said such lesions had appeared on the body since he was teenage.

Diagnosis?
Becker's naevus (Note the overlying hair).

Saturday, January 20, 2007

Derm round 6

Case 1
29 years old gentleman, presented with the above pruritic lesions of two years duration. He has been applying numerous creams he took from GP clinics as well as bought from the phamarcies.

Diannosis?
Tinea incognito.

More:
DermNet NZ.


Case 2

39 years old gentleman, with long-standing DM of more than 10 years, presented with the above lesions of 3 years duration. He is asymptomatic.

Diagnosis?
Pityriasis vesicolor.

More:
eMedicine